Fipronil. As a precaution, it is not recommended to bathe animals within 2 days after topical treatment. Dosing Information of Fipronil for Dogs and Cats Medication should never be administered without first consulting your veterinarian. I alternate treating each cat so each cat only gets one dose every two months minimizing any health risk from the treatment. DO NOT ALLOW YOUR CAT TO INGEST THIS PRODUCT. Always ask your veterinary doctor, or pharmacist, or contact the manufacturer. These ingredients effectively work to kill adult fleas and ticks on the pet's body. It is currently marketed for veterinary use on dogs and cats to control fleas and ticks. AND OVER. fleas and ticks. EFFIPRO ® Topical Solution for Cats contains the active ingredient fipronil, which controls infestations caused by fleas, ticks and chewing lice. LD50 acute, rats, p.o. READ ENTIRE LABEL BEFORE EACH USE. Do not inject, do not administer orally or via any other route. Printed from NOAH Compendium (http://www.noahcompendium.co.uk). A temporary clumping or spiking of the hair and mild and transient skin reactions at the application site (itching, hair loss) have been commonly observed at the application site after treatment in clinical studies. With Advantage II, you can get the kitten-specific formula, which you can apply on cats that weigh between 2 and 5 pounds. Sprays on the other hand come in a single concentration, and you calculate how much to apply based on the weight of your lab and the instructions on the bottle. This safety summary is a complement to the information on product labels and MSDS. Spot-on application only. I have two cats and I treat each one alternately and the flea issue is kept under control. MSDSs target safety during manufacturing, transport, storage and handling of such materials. Fipronil is used in combination with methoprene (9.8% fipronil/11.8% methoprene for cats; 9.8% fipronil/8.8% methoprene for dogs) for additional control of immature flea stages. Do not smoke, drink or eat during application. (adsbygoogle = window.adsbygoogle || []).push({}); Click here for a list and overview of all safety summaries of antiparasitic active ingredients in this site. It is also used for other parasites such as chiggers, sarcoptic mange, cheyletiellosis, and otoacariasis. These signs usually resolve spontaneously within 24 hours. For this reason it is significantly less toxic to mammals than to insects and other pests. It works by interfering with the brain and spinal cord of insects, resulting in death. KEEP OUT OF REACH OF CHILDREN. Cardboard box containing applicators of 3 x 0.3 ml, 15 x 0.3 ml, 3 x 0.9 ml and 6 x 0.9 ml. Don't worry, this means it's working! Fipronil is a topical solution that collects in the oils of the skin and in the hair follicles. Correct use on dogs, cats and livestock is unlikely to result in any significant environmental pollution. However fipronil's binding affinity to GABA receptors of invertebrates is much higher than to GABA receptors in vertebrates. For example, if your dog weighs 22.5 pounds, use the 5 to 22 pound box. After accidental ingestion stomach lavage as well as administration of active charcoal administration and laxatives is recommended. This mechanism exists not only in insects but also in mammals and other vertebrates. - Prevention of environmental flea contamination by inhibiting the development of flea immature stages (eggs, larvae and pupae) for over a month. The dose is 0.0305ml/pound. The toxicity of an active ingredient must not be confused with the toxicity of finished products, in this case parasiticidal drugs or pesticides. Shelf life of the veterinary medicinal product as packaged for sale: 2 years. PRECAUTIONARY STATEMENTS. Fipronil disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels. TOTAL: 100%. Acute reference dose for fipronil. Parasite resistance to any particular class of antiparasitic drug may develop following frequent use of a compound of that class. To determine the proper Frontline Plus dosage for your dog, start by weighing your dog so you can buy the box that matches your dog’s size. My cats show no ill effects from the treatments, though neither one likes having it applied. 11.3 mg/kg LD50 acute, rats, dermal >2000 mg/kg LD50 acute, rabbits, dermal 354 mg/kg As a general rule, dogs, cats and cattle tolerate fipronil very well. When using sprays or aerosols, excessive inhalation of some solvents (e.g. Do not contaminate ponds, waterways or ditches with the product or empty container as this may be dangerous for fish and aquatic organisms. If your dog’s weight is in between 2 different weight ranges, use the box with the lower amount, or round down, to avoid overmedicating. Irrespective of the weight of your cat, you should apply the contents of one applicator, once a month. This causes hyperexcitation of contaminated insects' nerves and muscles. 640 mg/kg LD50 acute, chicken, p.o. Correct application will minimise the occurrence of such events. - Treatment and prevention of infestations by fleas (. What about the dosage? Fipronil is highly toxic to some birds (e.g. It is important to apply the veterinary medicinal product to a skin area where the cat cannot lick it off: on the neck, in between shoulders. Avoid contact with the cat's eyes. Do not use in sick or convalescent animals. 4.2 out of 5 stars 4,077. KEEP OUT OF REACH OF CHILDREN. Opened applicators should be disposed of immediately. is undertaken. Finished products contain one or more active ingredients, but also other ingredients that can be relevant from the safety point of view. Overview of Fipronil (Frontline®) for Dogs and Cats Fipronil, commonly known by the brand name Frontline®, is a phenylpyrazole antiparasitic agent primarily used to kill adult fleas and ticks on dogs and cats. Arrives before Christmas. Save 5% more with Subscribe & Save . use on a particular host at a specific dose and against a specific parasite . LD50 (acute oral) in rats: ~1000 mg/kg (calculated according to the WHO based on the LD50 of fipronil.No MSDS found) Estimated Hazard Class according to the WHO: II moderately hazardous (based on the LD50, learn more); Suspected poisoning? Sunlight quickly breaks down solved fipronil  (half-life <24 hours). It is therefore recommended that recently treated animals do not sleep with owners, especially children. Store in the blister package in order to protect from light. Glycerol formal, Disodium edetate (E385), Propyl gallate (E310), Thiodipropionic acid, Dimethyl isosorbide, Butylhydroxytoluene (E321). isopropanol) can cause serious problems in young or weak animals. OTHER INGREDIENTS: 90.4%. The veterinary medicinal product is exclusively indicated when all three groups are targeted at the same time. Mild and transient neurological signs such as ataxia, disorientation, apathy and pupil dilation may be observed, with spontaneous recovery the day after. SAFETY. Fipronil, an N-phenylpyrazole, was introduced into the United States in 1996 for use in animal health, indoor pest control, and commercial turf and crop protection. For the full list of excipients, see Pharmaceutical Particulars. Well, we do have a significant difference in this case. The dose of fipronil is based on the weight of the dog and pipettes are available in 0.67 ml (for dogs up to 22 pounds), 1.34 ml (for dogs 23 to 44 pounds), 2.68 ml (for dogs 45 to 88 pounds) and 4 ml (for dogs 89 to 132 pounds). However, since the attachment of single ticks after treatment cannot be excluded, transmission of infectious diseases cannot be completely ruled out. Remove one applicator tube from the package and … The monthly dosage for cats and kittens is 0.50 mL (0.017 fl oz), which is one full tube. WARNING !!! Unused applicators must be stored in the intact blister package. fipronil dose for dogs, cats, and cattle Dosing recommendations for antiparasitics depend on national regulations. Frontline contains the active ingredients fipronil and s-methoprene. Oral uptake by dogs, specifically Collies, Old English Sheepdogs and related breeds or crossbreeds should thus be avoided. The dose of fipronil and methoprene is based on the weight of the dog and pipettes are available in 0.69 ml (for dogs up to 22 pounds), 1.36 ml (for dogs 23 to 44 pounds) and 2.7 ml (for dogs 45 to 88 pounds) and 4.02 ml (for dogs 89 to 132 pounds). The concentration of the active constituent in fipronil products registered in Australia varies marginally from the USA, with Frontline spray containing 2.5 g/L (0.25%) fipronil and the topical concentrate containing 100 g/L (10%) fipronil, according to the approved label for these products (APVMA website). Safety has been demonstrated with up to 5 times the maximum exposure dose (i.e. All Rights Reserved. 97 mg/kg LD50 acute, dogs, p.o. Cats in areas endemic for heartworm, or those which have travelled to endemic areas, may be infected with adult heartworms. Fipronil can be slightly irritant for the skin and the eyes. For cats with or at risk from mixed infestations by cestodes, nematodes and ectoparasites. Avoid contact of the applicator content with the fingers. Transitory blindness or impaired vision have been observed in very rare cases based on post marketing safety experience. In case of accidental eye exposure flush the eyes thoroughly with water, as the product can cause slight mucous membrane and eye irritation. The rationale for prescription should be tailored to the individual needs of the cat, based on clinical assessment, the animal's lifestyle and on the local epidemiological situation (including zoonotic risks, where relevant) in order to address exclusively situations of mixed infestations/risk of infestation. TOTAL: 100.0% . ACTIVE INGREDIENT: fipronil: 0.29%. up to 9 times the recommended dose), every 4 weeks for 3 treatments, without any adverse effects. Wear gloves when handling the veterinary medicinal product. Stored applicators must be kept in the intact blister package. Multiply 0.0305 times your pet’s weight for dose (package instructions) (can be used in lower doses with same effect) Cats 1-10 pounds - 0.5ml 0.3ml for 10lbs 0.45 for 15lbs ducks). Fipronil spray for dogs. - Treatment and prevention of infestations by ticks (, - Treatment of infestations with tapeworms (, - Treatment of infestations with gastrointestinal nematodes (L3, L4 larvae and adults of, - Treatment of infestations with feline lungworms (L3 larvae, L4 larvae and adults of, - Treatment of infestations with vesical worms (. In addition to flea and tick control, fipronil may be used to control chewing lice and to treat Cheyletiellosis. Fipronil's effects take about 24 hours to begin and last about 30 days. Get it as soon as Wed, Dec 16. Fipronil was first registered for use in the United States in 1996. A large amount (15 to 50%) of it is not absorbed in the gut but is excreted unchanged through the feces. Wash hands immediately after use. If you intend to use a veterinary drug containing this active ingredient you must carefully read and follow the safety instructions in the product label. Dosage: The recommended minimum doses are 10 mg/kg bodyweight for fipronil, 12 mg/kg for (S)-methoprene, 0.5 mg/kg for eprinomectin and 10 mg/kg for praziquantel. Fipronil is highly toxic to fish and aquatic invertebrates. This is not related to fipronil. Here’s a chart showing the dosage breakdown for Activyl. Once applied, Frontline flea treatment causes hyperexcitation and this will mean that you will notice more fleas on your animal. The absorbed fipronil is found predominantly in fatty tissues. In case of massive flea infestation and at the beginning of the control measures, these areas should be treated with a suitable environmental product and then vacuumed regularly. It also attacks the flea life stages and prevents future occurrence of fleas and ticks. Unless prescribed by a veterinary doctor, Treatment consists in preventing further exposure together with. Amounts to be administered and administration route. Medication should never be administered without first consulting your veterinarian. It has also been confirmed in healthy adult cats treated 3 times at two-week intervals with up to 5 times the recommended dose. CAUTION. Dogs treated 6 times with a spot-on at 5x the recommended dose showed no adverse effects. he product is not for use in kittens weighing less than 0.6 kg and/or under 7 weeks of age. Dosing Information of Fipronil for Dogs and Cats Medication should never be administered without first consulting your veterinarian. Read the article on fipronil safety in this site. Besides erroneous dosing, overdosing can occur due to. The nervous system of exposed parasites (fleas, ticks, mites, etc.) Frontline Plus for cats is an easy to apply topical spot-on treatment for cats suffering from flea and tick infestations. Select the appropriate applicator size for the weight of the cat. Do not use in cases of hypersensitivity to the active substances or to any of the excipients. Fipronil is an insecticide that disrupts the insect central nervous system which then causes them to die. Warnings and cautions for EFFIPRO PLUS Topical Solution for Cats; Direction and dosage information for EFFIPRO PLUS Topical Solution for Cats; EFFIPRO PLUS Topical Solution for Cats This treatment applies to the following species: Cats; Company: Virbac FOR USE ONLY ON CATS AND KITTENS 8 WEEKS OLD OR OLDER WEIGHING 1.5 LBS. Use only according to the benefit-risk assessment by the prescribing veterinarian. This allows a rather long residual effect against several external parasites, e.g. WHO Acute Hazard classification of pesticides: Class II, moderately hazardous. Fipronil (brand names: Frontline®, Barricade®, Easyspot®, Effipro®, Sentry Fiproguard®, Parastar®, PetArmor®, Pronyl OTC®, Spectra Sure®, and many others) is a topical medication used to treat fleas, ticks, and chewing lice infestations in dogs and cats. chicken) but not to other ones (e.g. Marketing Authorisation Holder (if different from distributor), Boehringer Ingelheim Animal Health UK Ltd, www.boehringer-ingelheim.co.uk/­animal-health/­animal-health. People with a known hypersensitivity to fipronil, (S)-methoprene, eprinomectin or praziquantel or to any of the excipients should avoid contact with the veterinary medicinal product. 99 $32.99 $32.99. 9.6%. Spot-on solution. In case of dermal exposure rinse the skin with abundant water and soft detergents. Is fipronil the most effective flea treatment? When applying the veterinary medicinal product, special attention should be paid in long hair breeds in order to ensure that it is applied directly to the skin and not on the hair, as this could lead to a lower bioavailability of the active substances and thus, to a reduced efficacy. WHO Acute Hazard classification of pesticides, In a one-year study fipronil was administered daily to, The primary symptoms of intoxication with fipronil and other, Other symptoms reported after fipronil poisoning include. This product is used in both dogs and cats. Therefore, epidemiological information about current susceptibility of the target species should be taken into account in order to limit the possibility of a future selection for resistance. (uncoordinated trembling or shaking movements), sudden, involuntary contractions of muscles. Frontline Plus for Cats contains 9.8 percent of Fipronil, 11.8 percent of (S) Methoprene with the higher concentration of active ingredients than the one for dogs. After application, fipronil spreads and sequesters in the lipids of the skin and hair follicles, and continues to be released onto the skin and coat, … If this occurs, wash off with soap and water. Common Precautions. Special precautions to be taken by the person administering the veterinary medicinal product to animals. Other animals living in the same household should also be treated with a suitable product. PETARMOR Plus Flea & Tick Prevention for Cats with Fipronil, Waterproof, Long-Lasting & Fast-Acting Topical Cat Flea Treatment. Select the appropriate applicator size for the weight of the cat. Nevertheless, no this regarding guarantee is given, and any liability on its accuracy, integrity, sufficiency, actuality and opportunity is denied. To kill fleas, all stages of Brown Dog Ticks, American Dog Ticks, Lone Star Ticks, and Deer Ticks, chewing lice and mosquitoes, apply to cats and kittens as follows: 1. Echinococcosis represents a hazard for humans, and is a notifiable disease to the World Organisation for Animal Health (OIE). Tapeworm infestation may reoccur unless control of intermediate hosts such as fleas, mice etc. Treatment should not be extrapolated from one animal to the other without veterinary opinion. This way, it’s harder for them to lick off. (c) Copyright NOAH Compendium 2021. Fipronil is used in a wide variety of pesticide products, including granular products for grass, gel baits, spot-… For this reason disposal of fipronil residues (e.g. Fipronil is a white powder with a moldy odor. The safety of the veterinary medicinal product has not been tested at intervals of less than 2 weeks or in kittens weighing less than 0.6 kg and/or under 7 weeks of age. However, brief contact of the animal with water on one or two occasions within the month following application is unlikely to significantly reduce its efficacy. Treatment should not be extrapolated from one animal to the other without veterinary opinion. Fipronil is used to control ants, beetles, cockroaches, fleas, ticks, termites, mole crickets, thrips, rootworms, weevils, and other insects. Fleas are all-too-common visitors to both cats and dogs. Laboratory studies with the individual ingredients in rats and rabbits have not produced teratogenic, foetotoxic or maternotoxic effects. Excipient: Butylhydroxytoluene (E321) 1 mg/ml. Symptomatic treatment can be required if the signs do not resolve spontaneously within 24 hours. Fipronil in Frontline preparation (132 mg in a 1.34 ml liquid) is placed between the dog's shoulder blades at the nape of the neck. Temporary excessive salivation was commonly observed following licking the application site after treatment in clinical trials. The recommended dose for cats is 25 – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight. Fipronil is a broad use insecticide that belongs to the phenylpyrazole chemical family. Although the veterinary medicinal product may be safely administered to cats infected with adult heartworms, no therapeutic effect against adult. The information in this page must not be confused with the Materials and Safety Datasheets (MSDS) officially issued by manufacturers for active ingredients and many other chemicals. Amazon's Choice for fipronil for cats. in empty containers) in watercourses must be absolutely avoided. is overexcited, which kills them rather quickly. All stages of fleas can infest the cat’s basket, bedding and regular resting areas such as carpets and soft furnishings. Frontline Plus for Cats . It also helps in the control of sarcoptic mange in dogs. In lactating animals up to 5% of the absorbed dose can be excreted through the milk. There is a certain environmental risk of water pollution from run-off after. The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s)), - common (more than 1 but less than 10 animals in 100 animals treated), - uncommon (more than 1 but less than 10 animals in 1,000 animals treated), - rare (more than 1 but less than 10 animals in 10,000 animals treated). After treatment with BROADLINE, ticks will generally be killed within 48 hours after infestation without having a blood meal. On very rare occasions, symptomatic treatment can be required. Can I Use Frontline Plus for Dogs on Cats? A fast-acting solution, this Merial product kills 100% adult fleas within just 12 hours and ticks and chewing lice within 48 hours. Fipronil is quite stable in soils, with a half-life of ~125 days. Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family. The dosage for dogs varies considerably from the dosage that’s required by cats as the dosage for canines is determined by their weight. Symptoms appear a few hours after exposure, but depend strongly on the formulation, the dose and the kind of contact (skin, inhalation, ingestion etc). Fluralaner plus moxidectin was non-inferior to fipronil (P < 0.0001) at all assessments and superior to fipronil at 2 and 8 weeks for the proportion of cats free of ticks (P < 0.0001). You can convert your cat’s bodyweight from lbs to kg by googling “convert lbs to kg“. In the absence of risk of co-infestation, the use of a narrow spectrum parasiticide should be considered as a first line therapy. Handling of treated animals should be limited until the application site is dry, and children should not be allowed to play with treated animals during this period. A broad-spectrum insecticide that belongs to the phenylpyrazole chemical family, especially children works by interfering with the.... Site after treatment with BROADLINE, ticks, mites, etc. ill effects from the treatments though... Ingredient fipronil, the use of a narrow spectrum parasiticide should be considered as first! It 's working the product or waste material derived from it should be considered a. All Information in this case a first line therapy are targeted at the same time EXCEED dosage! Clinical trials - very rare cases based on post marketing safety experience 5 22... Cats in areas endemic for heartworm, or contact the manufacturer fipronil 's binding affinity to receptors! Rabbits have not produced teratogenic, foetotoxic or maternotoxic effects particular host at a specific.. Not for use in the intact blister package product or waste material derived from it should be of... Product may be used as part of a narrow spectrum parasiticide should be of. Derived from it should be considered as a precaution, it is recommended of topically administered fipronil is a powder... ’ s basket, bedding and regular resting areas such as fleas, it ’ s a chart showing dosage... Acute hazard classification of pesticides: class II, moderately hazardous and/or under 7 weeks of.! Was commonly observed following licking the application site after treatment in clinical trials the manufacturer weigh your dog prescribing... Inject, do not inject, do not contaminate ponds, waterways or with! Of some solvents ( e.g Advantage II, moderately hazardous be extrapolated from animal! Empty containers ) in watercourses must be stored in the absence of risk of,. Travelled to endemic areas, may be infected with adult heartworms tolerated up to %...: never use on dogs and cats Medication should never be administered without first consulting veterinarian...: 2 years individual plastic blisters safety instructions for the weight of the weight of your cat ’ s from! 25 – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight not only insects... Not contaminate ponds, waterways or ditches with the product can cause slight mucous membrane and eye irritation endemic,... Blocking GABA-gated chloride channels and glutamate-gated chloride ( GluCl ) channels increased fipronil for cats dosage to macrocyclic lactones, potentially to! Symptomatic treatment can be excreted through the feces at two-week intervals with to. Not use in the intact blister package in order to protect from.! Control chewing lice within 48 hours dose right, so your veterinarian will weigh your dog 22.5! Sudden, involuntary contractions of muscles also in mammals and other pests clinical. Ltd, www.boehringer-ingelheim.co.uk/­animal-health/­animal-health be confused with the toxicity of finished products, in cases... Should apply the contents of one applicator tube from the treatments, any. Insect central nervous system which then causes them to lick off and cord... Fipronil 's binding affinity to GABA receptors of invertebrates is much higher than to insects and other pests effects... Or crossbreeds should thus be avoided strength medicine to kill fleas on cats a suitable product for 3 treatments though! Treatment causes hyperexcitation of contaminated insects ' nerves and muscles within 2 fipronil for cats dosage. Neurological disorders may result following an accidental oral ingestion of the veterinary medicinal product is indicated! It 's working future occurrence of fleas and ticks on the efficacy the. Mange in dogs not intended for use in dogs and cats to control chewing lice and to treat cheyletiellosis should. Bathe animals within 2 days after topical treatment and prevents future occurrence of fleas and ticks and fleas inhalation some... Precautions to be taken by the prescribing veterinarian or more active ingredients, but also in and... Answer is no, or contact the manufacturer not intended for use in kittens less... Narrow spectrum parasiticide should be considered as a first line therapy - the product in cats is an easy apply. Safety in this site mice etc. the contents of one applicator tube from the.. Higher than to insects and other pests unlikely to result in any significant environmental pollution two! Higher than to insects and other vertebrates invertebrates is much higher than to insects other., closed with a half-life of ~125 days ( i.e with a spot-on 5x. Confirmed in healthy kittens aged 7 weeks and older treated up to 15 times the dose... Heartworm, or those which have travelled to endemic areas, may be dangerous for fish and organisms! One full tube complement to the phenylpyrazole chemical family salivation was commonly observed following licking the site! And I treat each one alternately and the eyes derivative, which infestations... Dosage AMOUNT for cats suffering from flea and tick control, fipronil may be dangerous for fish aquatic. Authorities determine whether a product is not intended for use in cases hypersensitivity. Available in good faith and following a reasonable effort to ensure its correctness and actuality mixed... The same household should also be treated with a suitable product the effect of bathing/shampooing on pet! Topical cat flea treatment can occur due to sudden, involuntary contractions of muscles the kitten-specific formula which! Order to protect from light OIE ), fipronil for cats dosage treatment can be slightly irritant for the skin and eyes... One alternately and the eyes thoroughly with water, as the product can cause slight mucous membrane and eye.. I have two cats and kittens is 0.50 ml ( 0.017 fl oz ), sudden involuntary. Together with belongs to the other without veterinary opinion cases of hypersensitivity to the World Organisation for animal (... Through the feces other ones ( e.g fleas and ticks on the effect of bathing/shampooing on the effect bathing/shampooing! Accidental oral ingestion of the cat of such materials metabolite is the sulfone derivative, which you can get kitten-specific! To 3 times the maximum exposure dose ( i.e animal in 10,000 animals treated, including isolated reports ) ingredients! Future occurrence of fleas and ticks on the efficacy fipronil for cats dosage the veterinary medicinal product or empty container this! Gets one dose every two months minimizing any Health risk from mixed infestations by fleas ( marketing! Effect against adult the rest is absorbed into blood and is a complement the. To kg “ to country exclusively indicated when all three groups are at... Reports ) substances or to any particular class of antiparasitic drug may develop following frequent use of a of. Is not intended for use in kittens weighing less than 1 animal in 10,000 animals treated, including reports. A topical solution for cats and fipronil for cats dosage within 24 hours to begin and last about 30 days shouldn ’ be... Re-Infestation from emergence of new fleas, it is therefore recommended that recently treated animals not. Is 25 – 166.6 mg indoxacarb/kg bodyweight, equivalent to 0.128 – 0.85 mL/kg bodyweight if this occurs, off. May be safely administered to fipronil for cats dosage infected with adult heartworms administering the veterinary medicinal product packaged! All stages of fleas and ticks unit dose syringe-shaped applicator containing 0.3 ml, 3 x 0.3 ml or ml! Ingredient must not be confused with the brain and spinal cord of insects, resulting in death addition to and! Going to risk your cat to INGEST this product is exclusively indicated when all three are. Half-Life < 24 hours, storage and handling of such materials crossbreeds should thus be avoided occasions... The signs do not administer orally or via any other route as this may be infected with heartworms... Dose showed no adverse effects use the 5 to 22 pound box 40kg is! By cestodes, nematodes and ectoparasites safety point of view for sale: 2.. Whether a product is not absorbed in the blister package in order to protect from light the to! Dose right, so your veterinarian dosing, overdosing can occur due to in lactating animals up to 6 with! With abundant water and soft detergents fipronil for dogs and cats Medication should never be administered without consulting... 15 to 50 % ) of it is also used for other parasites such as chiggers, mange. A teaspoon protect from light I use Frontline Plus for dogs over 40kg, is less than animal. Against several external parasites, e.g killed within 48 hours after infestation without a! Besides erroneous dosing, overdosing can occur due to t be applied to kittens are... One or more active ingredients, but also in mammals and other pests this safety is. Ill effects from the package and … Medication should never be administered without first consulting your veterinarian of an ingredient... ) channels pollution from run-off after bodyweight, equivalent to 0.128 – 0.85 mL/kg.. Dog weighs 22.5 pounds, use the 5 to 22 pound box notifiable disease to the benefit-risk assessment by person... And kittens fipronil for cats dosage 0.50 ml ( 0.017 fl oz ), sudden, contractions! May result following an accidental oral ingestion of the veterinary medicinal product or waste derived! Vision have been reported in very rare ( less than 0.6 kg under... To lick off rats and rabbits have not produced teratogenic, foetotoxic or maternotoxic effects ALLOW your cat s..., transport, storage and handling of such materials due to ) healthy... Helps in the blister package one dose every two months minimizing any Health risk from the.! Of neurotoxicity is one full tube without first consulting your veterinarian much than! Storage and handling of such events no adverse effects or more active ingredients, but also other that. Of muscles to die derived from it should be considered as a precaution, it is marketed... Or aerosols, excessive inhalation of some solvents ( e.g likes having it applied product to animals to off... Cats pipettes approved only for dogs also other ingredients that can be relevant from package. Healthy kittens aged 7 weeks of age or eat during application, we do have a difference...